Extrinsic Pathway (Last Updated - 2/27/2005)

-involves tissue factor (TF), thromboplastin, Factors VII & VIIa
-a deficiency of any of the above factors will lead to prolongation of the PT
-click here to view an image of the clotting cascade

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References:

Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.